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Dietary Glycemic Index, Glycemic Load, and Cancer Risk: Results from the EPIC-Italy Study:

Science News, presented by the Glycemic Research Institute®

Findings: Factors linked to glucose metabolism are involved in the etiology of several cancers.

High glycemic index (GI) or high glycemic load (GL) diets, which chronically raise postprandial blood glucose, may increase cancer risk by affecting insulin-like growth factor.

We prospectively investigated cancer risk and dietary GI/GL in the EPIC-Italy cohort. After a median 14.9 years, 5112 incident cancers and 2460 deaths were identified among 45,148 recruited adults. High GI was associated with increased risk of colon and bladder cancer.


High GL was associated with: increased risk of colon cancer; increased risk of diabetes-related cancers. High intake of carbohydrate from high GI foods was significantly associated with increased risk of colon and diabetes-related cancers, Low Glycemic foods were associated with reduced colon cancer risk.


In a Mediterranean population with high and varied carbohydrate intake, carbohydrates that strongly raise postprandial blood glucose may increase colon and bladder cancer risk, while the quantity of carbohydrate consumed may be involved in diabetes-related cancers.

Reference: NATURE.COM- S. Sieri et al


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